AMD平台这几年坚持一个AM4封装接口，理论上新老主板、处理器都可以完全兼容，只是受制于技术、非技术的多方面原因，并不会跨越太多代际。

比如最新的锐龙5000系列处理器，就只有400、500系列主板支持，包括B450、X470、A520、B550、X570五款型号。

各家的500系列主板已经全部支持锐龙5000，对应的AGESA微代码都是1.1.0.0版本。

400系列主板原计划在明年1月前陆续支持，但厂商们动作更快，绝大部分都已经给出BIOS，只不过有的是基于1.1.0.0版微代码的正式版，有的还是基于1.0.8.0系列的测试版(包括1.0.8.0/1/3)，后者还未释放全部性能。

还有一部分400系列主板暂未获得新BIOS，包括华擎的X470，映泰的B450、X470，微星的部分B450、X470。

总的来说，目前已有246款400、500系列主板确认可以支持锐龙5000系列，涵盖华硕、华擎、映泰、技嘉、微星等品牌，完整名单如下：

华硕B450 (1.0.8.0)

Prime B450M-A

Prime B450M-A II

Prime B450M-K

Prime B450-Plus

TUF B450M-Plus Gaming

TUF Gaming B450M-Plus II

TUF B450M-Pro Gaming

TUF Gaming B450M-Pro II

TUF B450M-Pro S.

TUF B450-Plus Gaming

TUF B450-Pro Gaming

ROG Strix B450-F Gaming

ROG Strix B450-F Gaming II

ROG Strix B450-E Gaming

ROG Strix B450-I Gaming

华硕X470 (1.0.8.0)

Prime X470-Pro

TUF X470-Plus Gaming

ROG Strix X470-F Gaming

ROG Strix X470-I Gaming

ROG Crosshair VII Hero

ROG Crosshair VII Hero (Wi-Fi)

华硕A520 (1.1.0.0)

Prime A520-A

Prime A520M-E

Prime A520M-K

Pro A520M-C/CSM

TUF Gaming A520M-Plus

华硕B550 (1.1.1.0)

Prime B550M-K

Prime B550M-A

Prime B550M-A (Wi-Fi)

Prime B550-Plus

TUF Gaming B550M-Plus

TUF Gaming B550M-Plus (Wi-Fi)

TUF Gaming B550-Plus

ROG Strix B550-A Gaming

ROG Strix B550-I Gaming

ROG Strix B550-F Gaming

ROG Strix B550-F Gaming (Wi-Fi)

ROG Strix B550-E Gaming

ROG Strix B550-XE Gaming (Wi-Fi)

华硕X570 (1.1.0.0)

Prime X570-P

Prime X570-Pro

Pro WS X570-ACE

TUF Gaming X570-Plus

TUF Gaming X570-Plus (Wi-Fi)

TUF Gaming X570-Pro (Wi-Fi)

ROG Strix X570-E Gaming

ROG Strix X570-F Gaming

ROG Strix X570-I Gaming

ROG Crosshair VIII Impact

ROG Crosshair VIII Hero

ROG Crosshair VIII Dark HERO

ROG Crosshair VIII Hero (Wi-Fi)

ROG Crosshair VIII Formula

华擎B450 (1.1.0.0)

B450M/ac

B450M/ac R2.0

B450M Pro4

B450M Pro4 R2.0

B450M Pro4-F

B450M Steel Legend

B450M-HDV

B450M-HDV R4.0

B450 Pro4

B450 Pro4 R2.0

B450 Steel Legend

Fatal1ty B450 Gaming K4

Fatal1ty B450 Gaming-ITX/ac

华擎X470

X470 D4U

X470 D4U2-2T

X470 Master SLI

X470 Master SLI/ac

Fatal1ty X470 Gaming K4

Fatal1ty X470 Gaming-ITX/ac

X470 Taichi

X470 Taichi Ultimate

华擎A520 (1.1.0.0)

A520M Pro4

A520M-HDV

A520M-HVS

A520M-ITX/ac

华擎B550 (1.1.0.0)

B550M/ac

B550M-HDV

B550M Pro4

B550M Phantom Gaming 4

B550M ITX/ac

B550M Steel Legend

B550 Pro4

B550 Extreme4

B550 Phantom Gaming 4

B550 Phantom Gaming 4/ac

B550 Phantom Gaming-ITX/ax

B550 PG Velocita

B550 Steel Legend

B550 Taichi

B550 Taichi Razer Edition

华擎X570 (1.1.0.0)

X570M Pro4

X570 Phantom Gaming 4

X570 Phantom Gaming 4 Wi-Fi ax

X570 Phantom Gaming 4S

X570 Phantom Gaming X

X570 PG Velocita

X570 Phantom Gaming-ITX/TB3

X570 Steel Legend

X570 Steel Legend Wi-Fi ax

X570 Pro4

X570 Extreme4

X570 Extreme4 Wi-Fi ax

X570 Taichi

X570 Taichi Razer Edition

X570 Creator

X570 AQUA

映泰B450

B450MHC

B450MH

B450NH

B450GT3

B450GT

映泰X470

X470 X470MH

X470NH

X470GTA

X470GTN

X470GTQ

X470GT8

映泰A520 (1.1.0.0)

A520MH

映泰B550 (1.1.0.0)

B550MH

B550GTA

B550GTQ

映泰X570 (1.1.0.0)

X570GT

X570GT8

X570GTA

技嘉B450 (1.1.0.0)

B450M H

B450M S2H

B450M S2H V2

B450M Gaming

B450M DS3H

B450M DS3H V2

B450M DS3H Wi-Fi

B450M Aorus Elite

B450 Aorus M

B450 Aorus Pro

B450 Aorus Pro Wi-Fi

B450 Gaming X

B450 Aorus Elite

B450 Aorus Elite V2

B450 I Aorus Pro Wi-Fi

技嘉X470 (1.1.0.0)

X470 Aorus Gaming 5 Wi-Fi

X470 Aorus Gaming 7 Wi-Fi

X470 Aorus Gaming 7 Wi-Fi-50

X470 Aorus Ultra Gaming

技嘉A520 (1.1.0.0)

A520M H

A520M S2H

A520M DS3H

A520 Aorus Elite

A520I AC

技嘉B550 (1.1.0.0)

B550M H

B550M S2H

B550M DS3H

B550M DS3H AC

B550M Gaming

B550 Gaming X

B550 Gaming X V2

B550M Aorus Elite

B550M Aorus Pro

B550M Aorus Pro-P

B550I Aorus Pro AX

B550 Aorus Pro

B550 Aorus Pro AC

B550 Aorus Pro AX

B550 Aorus Pro V2

B550 Aorus Elite

B550 Aorus Elite V2

B550 Aorus Elite AX

B550 Aorus Elite AX V2

B550 Aorus Master

B550 Vision D

技嘉X570 (1.1.0.0)

X570 UD

X570 Gaming X

X570 Aorus Pro

X570 Aorus Pro Wi-Fi

X570 Aorus Elite

X570 Aorus Elite Wi-Fi

X570 Aorus Ultra

X570 Aorus Master

X570 Aorus Xtreme

X570 I Aorus Pro Wi-Fi

微星B450 (1.1.0.0)

B450M-A Pro MAX

B450M Pro-VDH

B450M Pro-VDH MAX

B450M Pro-VDH V2

B450M Pro-VDH Plus

B450M Pro-M2

B450M Pro-M2 MAX

B450M Pro-M2 V2

B450M Mortar

B450M Mortar MAX

B450M Mortar Titanium

B450M Gaming Plus

B450M Bazooka

B450M Bazooka MAX Wi-Fi

B450M Bazooka V2

B450M Bazooka Plus

B450I Gaming Plus AC

B450I Gaming Plus MAX Wi-Fi

B450-A Pro

B450-A Pro MAX

B450 Tomahawk

B450 Tomahawk MAX

B450 Tomahawk MAX II

B450 Gaming Plus

B450 Gaming Plus MAX

B450 Gaming Pro Carbon AC

微星X470 (1.1.0.0)

X470 Gaming Plus

X470 Gaming Plus MAX

X470 Gaming Pro

X470 Gaming Pro MAX

X470 Gaming Pro Carbon

X470 Gaming Pro Carbon AC

X470 Gaming M7 AC

微星A520 (1.1.0.0)

A520M Pro

A520M-A Pro

MAG A520M Vector Wi-Fi

微星B550 (1.1.0.0)

B550M-A Pro

B550M Pro-DASH

B550M Pro-VDH

B550M Pro-VDH Wi-Fi

B550M Pro

B550-A Pro

MAG B550M Bazooka

MAG B550M Mortar

MAG B550M Mortar Wi-Fi

MAG B550M Vector Wi-Fi

MAG B550 Tomahawk

MAG B550 torpedo

MAG B550 Gaming Plus

MPG B550 Gaming Edge Wi-Fi

MPG B550 Gaming Carbon Wi-Fi

MPG B550I Gaming Edge Wi-Fi

MPG B550I Gaming Edge MAX Wi-Fi

MEG B550 Unify

MEG B550 Unify-X

微星X570 (1.1.0.0)

X570-A PRO

MAG X570 Tomahawk Wi-Fi

MEG X570 Ace

X570 Unify

MEG X570 Godlike

MPG X570 Gaming Plus

MPG X570 Gaming Edge Wi-Fi

MPG X570 Gaming Pro Carbon Wi-Fi

Prestige X570 Creatio